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Kanamycin sulfate from Streptomyces kanamycetikus, MP Biomedicals™
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Quantity:
1 g
5 g
25 g
100 g
Description
- It is a broad spectrum aminoglycoside-antibiotic derived from Streptomyces kanamyceticus.
- It is used as an additive in culture media for the isolation of group D streptococci on Kanamycin Esculin Azide Agar and for selection of transformed plant cells containing the neomycin phosphotransferase on a kanamycin-medium.
- Kanamycin sulfate can also be used as a selection agent for cells transformed with kanamycin B resistance gene.
- Kanamycin sulfate is an antimicrobial agent effective against Gram-negative and Gram-positive bacteria and mycoplasma.
- It binds to the 70S ribosomal subunit, inhibits translocation, and elicits miscoding.
- Cross-resistance occurs between kanamycin and neomycin, framycetin, and paromomycin, and partial cross-resistance has been reported between kanamycin and streptomycin. Aminoglycosidemodifying enzymes (acetyltransferase, phosphotransferase, nucleotidyltransferase) alter the antibiotic, preventing its interaction with ribosomes.

Specifications
Specifications
Physical Form | Powder |
pH | 6.5 to 8.5 (1% solution) |
Melting Point | >250°C |
Loss on Drying | <4% |
Potency | >750 µg/mg |
Color | White |
Quantity | 100 g |
Solubility Information | Soluble in 10-50mg/mL of Water |
Grade | USP |
Safety and Handling
RTECSNumber | NZ3225030 |
storageNote1 | Store at Room Temperature (15-30°C). |
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