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  6. Kanamycin sulfate from Streptomyces kanamycetikus, MP Biomedicals™

Kanamycin sulfate from Streptomyces kanamycetikus, MP Biomedicals™

Catalog No. MP219985380 Shop All MP Biomedicals, Inc Products
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Description

Kanamycin sulfate from Streptomyces kanamycetikus USP Grade, White Powder

  • It is a broad spectrum aminoglycoside-antibiotic derived from Streptomyces kanamyceticus.
  • It is used as an additive in culture media for the isolation of group D streptococci on Kanamycin Esculin Azide Agar and for selection of transformed plant cells containing the neomycin phosphotransferase on a kanamycin-medium.
  • Kanamycin sulfate can also be used as a selection agent for cells transformed with kanamycin B resistance gene.
  • Kanamycin sulfate is an antimicrobial agent effective against Gram-negative and Gram-positive bacteria and mycoplasma.
  • It binds to the 70S ribosomal subunit, inhibits translocation, and elicits miscoding.
  • Cross-resistance occurs between kanamycin and neomycin, framycetin, and paromomycin, and partial cross-resistance has been reported between kanamycin and streptomycin. Aminoglycosidemodifying enzymes (acetyltransferase, phosphotransferase, nucleotidyltransferase) alter the antibiotic, preventing its interaction with ribosomes.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 25389-94-0
Molecular Formula C18H38N4O15S
Molecular Weight (g/mol) 582.58
MDL Number MFCD00070253
InChI Key OOYGSFOGFJDDHP-KMCOLRRFSA-N
Synonym Kanamycin A, Kanamycin sulfate salt
PubChem CID 134129479

Specifications

Physical Form Powder
pH 6.5 to 8.5 (1% solution)
Melting Point >250°C
Loss on Drying <4%
Potency >750 µg/mg
Color White
Quantity 100 g
Solubility Information Soluble in 10-50mg/mL of Water
Grade USP

Safety and Handling

RTECSNumber NZ3225030
storageNote1 Store at Room Temperature (15-30°C).
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