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Medchemexpress LLC Kasugamycin (hydrochloride) | 19408-46-9 | 99.95% | 25 MG
Supplier: Medchemexpress LLC 25MGHYB1864A
Kasugamycin hydrochloride hydrate is an antibiotic that binds to 30s and 70s ribosomes (but not to the 50s subunit), and exhibits anti-infective activity. It mimics mRNA nucleotides, disrupting tRNA binding and inhibiting canonical translation initiation. It also increases the sensitivity of mycobacteria to Rifampicin in vitro and in mouse infection models.
- Antibiotic that binds to 30s and 70s ribosomes
- Mimics mRNA nucleotides
- Disrupts tRNA binding
- Inhibits canonical translation initiation
- Increases sensitivity of mycobacteria to Rifampicin
- Solid, off-white to light yellow appearance
- Anti-infective activity
- Potentiates Rifampicin and limits emergence of resistance in *Mycobacterium tuberculosis*
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