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Medchemexpress LLC Kasugamycin hydrochloride hydrate | 200132-83-8 | 99.9% | 1 ML
Supplier: Medchemexpress LLC HYB1864B10MM/1ML
Kasugamycin (Ksg) hydrochloride hydrate is an antibiotic that binds to 30s and 70s ribosomes, exhibiting anti-infective activity. It disrupts tRNA binding by mimicking mRNA nucleotides, which inhibits canonical translation initiation. This compound also increases the sensitivity of mycobacteria to Rifampicin both in vitro and in mouse infection models.
- Antibiotic with anti-infective activity
- Binds to 30s and 70s ribosomes
- Mimics mRNA nucleotides, disrupting tRNA binding
- Inhibits canonical translation initiation
- Increases sensitivity of mycobacteria to Rifampicin
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