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Medchemexpress LLC Kavain | 3155-48-4 | 100 MG
SDP

Supplier:  Medchemexpress LLC HYN2096100MG

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Kavain is a class of kavalactone isolated from *Piper methysticum*, which has anxiolytic properties in animals and humans. It positively modulates γ-Aminobutyric acid type A (GABAA) receptor. In vitro, Kavain positively modulates all GABAA receptors regardless of subunit composition, with a greater enhancement at α4β2δ than at α1β2γ2L GABAARs. Its modulatory effect is not affected by flumazenil, indicating it does not enhance GABAARs via the classical benzodiazepine binding site.

  • Isolated from *Piper methysticum*
  • Exhibits anxiolytic properties
  • Positively modulates γ-Aminobutyric acid type A (GABAA) receptors
  • Modulatory effect not affected by flumazenil

Catalog No. 50-004-21872


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