Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000351837

Medchemexpress LLC KB-0742 dihydrochloride | 2416874-75-2 | 98.77% | 360.33 | 25 MG
SDP

Catalog No. 5000351837
Encompass_Preferred

KB-0742 dihydrochloride is a potent, selective, and orally active CDK9 inhibitor with an IC50 of 6 nM for CDK9/cyclin T1. It shows >50-fold selectivity over other CDK kinases and exhibits potent anti-tumor activity.

  • Potent and selective CDK9 inhibitor.
  • Orally active.
  • Exhibits >50-fold selectivity over other CDK kinases.
  • Possesses potent anti-tumor activity.
  • Reduces downstream phosphorylation of RNA Pol II.
  • Downregulates global androgen receptor (AR) protein levels.
  • Decreases nascent transcription and depletes short half-life transcripts.
  • Well tolerated and significantly reduces tumor burden in xenograft models.

Catalog No. 50-003-51837 Supplier Medchemexpress LLC Supplier No. 25MGHY137478A
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

KB-0742 dihydrochloride is a potent, selective, and orally active CDK9 inhibitor with an IC50 of 6 nM for CDK9/cyclin T1. It shows >50-fold selectivity over other CDK kinases and exhibits potent anti-tumor activity.

  • Potent and selective CDK9 inhibitor.
  • Orally active.
  • Exhibits >50-fold selectivity over other CDK kinases.
  • Possesses potent anti-tumor activity.
  • Reduces downstream phosphorylation of RNA Pol II.
  • Downregulates global androgen receptor (AR) protein levels.
  • Decreases nascent transcription and depletes short half-life transcripts.
  • Well tolerated and significantly reduces tumor burden in xenograft models.

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.