Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC KB-0742 dihydrochloride | 2416874-75-2 | 98.8% | 360.33 | 10 MG
Supplier: Medchemexpress LLC 10MGHY137478A
KB-0742 dihydrochloride is a potent, selective, and orally active CDK9 inhibitor with an IC50 of 6 nM for CDK9/cyclin T1. It exhibits significant selectivity over other CDK kinases and demonstrates potent anti-tumor activity.
- Potent, selective, and orally active CDK9 inhibitor
- Shows over 50-fold selectivity for CDK9/cyclin T1
- Exhibits potent anti-tumor activity
- Significantly reduces downstream phosphorylation of RNA Pol II
- Reduces global androgen receptor protein levels
- Shows cytostatic effects in prostate cancer and leukemia cell lines
- Well tolerated and reduces tumor burden in xenograft models
- Soluble in H2O and DMSO
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?