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Medchemexpress LLC KB-5492 (anhydrous) | 129200-10-8 | 99.5% | 546.57 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY191205MG

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KB-5492 anhydrous is a potent and selective inhibitor of the sigma receptor, inhibiting specific [3H]1,3-di(2-tolyl)guanidine (DTG) binding with an IC50 of 3.15 μM. It also functions as an anti-ulcer agent, preventing ethanol- and acidified aspirin-induced increases in 51Cr release from gastric epithelial cells in vitro, and macroscopic lesions in the gastric mucosa in vivo.

  • Potent and selective sigma receptor inhibitor
  • Inhibits specific DTG binding in a concentration-dependent manner
  • Prevents ethanol- and acidified aspirin-induced increases in 51Cr release from gastric epithelial cells
  • Prevents macroscopic lesions in the gastric mucosa in animal models
  • Suitable for research use only

Catalog No. 50-003-85063


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