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Apexbio Technology LLC kb NB 142-70 1233533-04-4 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC A35245.1
kb NB 142-70 (CAS 1233533-04-4) is a small molecule inhibitor that exhibits selectivity toward protein kinase D (PKD) isoforms with reported IC50 values of 28 3 nM for PKD1 58 7 nM for PKD2 and 53 2 nM for PKD3 By targeting PKD activity kb NB 142-70 has been shown to suppress prostate cancer cell migration and invasion as well as impair wound healing processes in vitro Additionally it demonstrates pronounced cytotoxic and anti-proliferative properties in cellular assays This compound is utilized in research to investigate PKD-related signaling pathways and to explore therapeutic strategies targeting cancer cell proliferation and metastatic behavior
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