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Cayman Chemical kb NB 142-70 50mg
Supplier: Cayman Chemical 1800250 MG
An inhibitor L-type CaV channels selective for CaV1.2 over CaV1.3 channels (IC50s 0.139 and 2.7 UM respectively) as well as R- N- and P/Q-type Cav channels at 10 UM inhibits contractions induced by potassium but not norepinephrine in isolated rabbit aortic strips from 0.72-24 nM increases cerebral blood flow in anesthetized dogs when administered sublingually from 0.01-1 mg/kg decreases necrosis of hippocampal CA1 pyramidal neurons and reduces increases in spontaneous movement and contralateral circling in a rat model of focal cerebral ischemia induced by MCAO
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