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ABclonal Technology KD Validated COX7A2L
Supplier: ABclonal Technology A2598020UL
Cytochrome c oxidase (COX) a key component of the mitochondrial respiratory chain transfers electrons from cytochrome c to oxygen It is a heteromeric complex with 3 mitochondrial-encoded catalytic subunits and several nuclear-encoded structural subunits which regulate and assemble the complex This gene encodes a protein similar to subunit VIIa polypeptides and mouse Sig81 protein It is expressed in all tissues and upregulated in a breast cancer cell line after estrogen treatment suggesting a role as a regulatory subunit of COX enhancing energy production in target cells Multiple transcript variants including protein-coding and non-coding forms exist for this gene
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