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Enzo Life Sciences Kenpaullone (5mg). CAS: 142273-20-9
Supplier: Enzo Life Sciences BMLEI3100005
Potent inhibitor of CDK1/cyclin B (IC50=400nM). Also inhibits CDK2/cyclin A (IC50=680nM) , CDK5 (IC50=850nM) and with much less effect other kinases. More recently, kenpaullone has been found to be a useful GSK-3β inhibitor (IC50=23nM). Induces pluripotency in somatic cells when used in combination with reprogramming factors. Increases neurogenesis of human neural progenitor cells through stimulation of Wnt/β-catenin signaling pathway. Alternative name: 9-Bromo-7,12-dihydroindolo-[3,2-d][1]benzazepin-6(5H)-one. Purity: ≥98% (TLC). Solubility: Soluble in DMSO (>25mg/ml); insoluble in water or ethanol. Long Term Storage: -20°C.
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