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Medchemexpress LLC Ketoconazole | 65277-42-1 | 99.6% | C26H28Cl2N4O4 | 25 MG
SDP

Catalog No. 5000359040
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Ketoconazole (R-41400) is an imidazole anti-fungal agent and an inhibitor of CYP3A4 and CYP24A1. It is for research use only. In studies, it has been observed to inhibit hepatic CYP450 and CYT b5 activities, enhance antiproliferative effects, and promote caspase-independent apoptosis pathways. It is also a potent exosome biogenesis and/or secretion inhibitor.

  • Inhibits hepatic CYP450 and CYT b5 activities
  • Enhances antiproliferative effects and increases systemic calcitriol exposure
  • Promotes activation of caspase-independent apoptosis pathways
  • Potent exosome biogenesis and/or secretion inhibitor
  • Used in histological imaging/staining, cell proliferation/viability assays, and in vivo efficacy studies
  • Assesses lipid peroxidation and cell viability
  • Pre-treats primary mouse hepatocytes to measure PEPCK1 protein levels

Catalog No. 50-003-59040 Supplier Medchemexpress LLC Supplier No. 25MGHYB0105B
May include imposed supplier surcharges.
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Ketoconazole (R-41400) is an imidazole anti-fungal agent and an inhibitor of CYP3A4 and CYP24A1. It is for research use only. In studies, it has been observed to inhibit hepatic CYP450 and CYT b5 activities, enhance antiproliferative effects, and promote caspase-independent apoptosis pathways. It is also a potent exosome biogenesis and/or secretion inhibitor.

  • Inhibits hepatic CYP450 and CYT b5 activities
  • Enhances antiproliferative effects and increases systemic calcitriol exposure
  • Promotes activation of caspase-independent apoptosis pathways
  • Potent exosome biogenesis and/or secretion inhibitor
  • Used in histological imaging/staining, cell proliferation/viability assays, and in vivo efficacy studies
  • Assesses lipid peroxidation and cell viability
  • Pre-treats primary mouse hepatocytes to measure PEPCK1 protein levels

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