Ketoprofen

Description

A non-steroidal anti-inflammatory drug (NSAID); also inhibits cyclooxygenases-1 and -2 | CAS: 22071-15-4 | C16H14O3 | 254.285 g/mol

It is used as a anti-inflammatory; analgesic and an antipyretic drug cause the hypothalamus to override an interleukin-induced increase in temperature. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is used as a anti-inflammatory; analgesic and an antipyretic drug cause the hypothalamus to override an interleukin-induced increase in temperature. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.

Solubility
Slightly soluble in chloroform and methanol.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Specifications

Chemical Identifiers

• CAS: 22071-15-4
• Molecular Formula: C16H14O3
• Molecular Weight (g/mol): 254.285
• MDL Number: MFCD00055790
• InChI Key: DKYWVDODHFEZIM-UHFFFAOYSA-N
• Synonym: ketoprofen, 2-3-benzoylphenyl propanoic acid, orudis, m-benzoylhydratropic acid, 2-3-benzoylphenyl propionic acid, ketoprofene, profenid, oruvail, 3-benzoylhydratropic acid, alrheumat
• PubChem CID: 3825
• ChEBI: CHEBI:6128
• IUPAC Name: 2-(3-benzoylphenyl)propanoic acid
• SMILES: CC(C1=CC=CC(=C1)C(=O)C2=CC=CC=C2)C(=O)O

• Melting Point: 92°C to 97°C
• Color: White
• Quantity: 5 g
• UN Number: UN2811
• Merck Index: 14,5305
• Solubility Information: Slightly soluble in chloroform and methanol.
• Formula Weight: 254.29
• Physical Form: Powder
• Chemical Name or Material: Ketoprofen

Safety and Handling

Hazard Category	H301
Hazard Statement	GHS H Statement H301-H315-H319-H335 Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P264b-P270-P301+P310-P330-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber	244-759-8
RTECSNumber	UE7570000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only