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Ketoprofen

Catalog No. AAJ6270214
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Catalog No. AAJ6270214 Supplier Thermo Scientific Chemicals Supplier No. J6270214
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A non-steroidal anti-inflammatory drug (NSAID); also inhibits cyclooxygenases-1 and -2 | CAS: 22071-15-4 | C16H14O3 | 254.285 g/mol

It is used as a anti-inflammatory; analgesic and an antipyretic drug cause the hypothalamus to override an interleukin-induced increase in temperature. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is used as a anti-inflammatory; analgesic and an antipyretic drug cause the hypothalamus to override an interleukin-induced increase in temperature. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.

Solubility
Slightly soluble in chloroform and methanol.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 22071-15-4
Molecular Formula C16H14O3
Molecular Weight (g/mol) 254.285
MDL Number MFCD00055790
InChI Key DKYWVDODHFEZIM-UHFFFAOYSA-N
Synonym ketoprofen, 2-3-benzoylphenyl propanoic acid, orudis, m-benzoylhydratropic acid, 2-3-benzoylphenyl propionic acid, ketoprofene, profenid, oruvail, 3-benzoylhydratropic acid, alrheumat
PubChem CID 3825
ChEBI CHEBI:6128
IUPAC Name 2-(3-benzoylphenyl)propanoic acid
SMILES CC(C1=CC=CC(=C1)C(=O)C2=CC=CC=C2)C(=O)O

Specifications

Melting Point 92°C to 97°C
Color White
Quantity 25 g
UN Number UN2811
Merck Index 14,5305
Solubility Information Slightly soluble in chloroform and methanol.
Formula Weight 254.29
Physical Form Powder
Chemical Name or Material Ketoprofen
Hazard Category H301
Hazard Statement GHS H Statement
H301-H315-H319-H335
Toxic if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P264b-P270-P301+P310-P330-P501c
DOTInformation Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber 244-759-8
RTECSNumber UE7570000
TSCA Yes
Recommended Storage Ambient temperatures

RUO – Research Use Only

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