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Medchemexpress LLC Kevetrin hydrochloride | 66592-89-0 | 98.0% | 179.67 | 50MG
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Supplier:  Medchemexpress LLC HY1627150MG

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Kevetrin hydrochloride is a potent activator of p53, inducing apoptosis in both TP53 wild-type and mutant acute myeloid leukemia cells. This compound demonstrates preferential cytotoxic activity against blast cells and is intended for research use only.

  • Potent activator of p53.
  • Induces apoptosis in TP53 wild-type and mutant acute myeloid leukemia cells.
  • Exhibits preferential cytotoxic activity against blast cells.
  • Significantly inhibits KASUMI-1 cell growth.
  • Induces metallothionein (MT) expression in acute myeloid leukemia cells.
  • Increases p53 mRNA and protein levels, and induces p21 protein production.
  • Inhibits tumor growth and extends survival time in xenograft models.

Catalog No. 50-003-92125


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