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Medchemexpress LLC Kinesore | 363571-83-9 | 98.0% | 536.17 | 50 MG
Supplier: Medchemexpress LLC HY11277750MG
Kinesore is an inhibitor of the KLC2-SKIP Interaction. It induces the reorganization of the microtubule network and the formation of extensive microtubule-rich projections, and this effect is dependent upon the presence of kinesin-1. The effect is reversible. This reorganization is observed in a panel of mammalian normal and cancer cell lines.
- Inhibitor of the KLC2-SKIP Interaction
- Reorganizes the microtubule network into loops and bundles
- Accumulates the lysosomal compartment in a juxtanuclear position
- Effect is apparent at 25 μM and reversible
- Observed in various mammalian normal and cancer cell lines
- Microtubule remodeling is dependent on kinesin-1
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