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Medchemexpress LLC KJ Pyr 9 | 581073-80-5 | 99.6% | 385.37 | 5 MG
Supplier: Medchemexpress LLC 5MGHY19735
KJ Pyr 9 is an inhibitor of MYC, interfering with MYC-MAX complex formation and inhibiting oncogenic transformation. It reduces the MYC-driven transcriptional signature and inhibits the proliferation of various cell lines, with higher sensitivity for Burkitt lymphoma cell lines. In vivo, it demonstrates the ability to halt tumor growth.
- Interferes with MYC-MAX complex formation
- Inhibits MYC-induced oncogenic transformation in cell culture
- Reduces the MYC-driven transcriptional signature
- Inhibits proliferation of NCI-H460, MDA-MB-231, and SUM-159PT cell lines
- More sensitive for Burkitt lymphoma cell lines with high c-MYC expression
- Halts tumor growth in vivo at 10 mg/kg
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