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Medchemexpress LLC KL-11743 | 1369452-53-8 | 99.4% | C30H30N6O3 | 50 MG
Supplier: Medchemexpress LLC HY14559750MG
KL-11743 is a potent, orally active, and glucose-competitive inhibitor of class I glucose transporters (GLUT1, GLUT2, GLUT3, and GLUT4). It blocks glucose metabolism and can synergize with electron transport inhibitors to induce cell death. Additionally, KL-11743 induces the formation of disulfide bonds in actin cytoskeletal proteins, leading to cellular disulfidptosis.
- Potent, orally active, and glucose-competitive inhibitor of class I glucose transporters
- Blocks glucose metabolism and synergizes with electron transport inhibitors to induce cell death
- Induces cellular disulfidptosis
- Inhibits the growth of various cancer cell lines in vitro
- Effective in decreasing tumor growth in animal models
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