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Apexbio Technology LLC KN-92 hydrochloride 1431698-47-3 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC A35305.1
KN-92 hydrochloride is an inactive structural analog of the Ca /calmodulin-dependent protein kinase II (CaMKII) inhibitor KN-93 serving primarily as a comparative control compound in biological research Unlike KN-93 KN-92 hydrochloride lacks meaningful inhibitory activity against CaMKII exhibiting a much higher Ki value ( 100 M) In experimental models it is utilized to distinguish CaMKII-dependent molecular and physiological responses particularly in studies of early afterdepolarizations (EADs) and cardiac repolarization events Based on these properties KN-92 hydrochloride is applied as a negative control in cardiac electrophysiological research
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