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ABclonal Technology KO Validated Claudin 1
SDP

Catalog No. 5000005180
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Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet with complementary grooves in the inwardly facing extracytoplasmic leaflet The protein encoded by this gene a member of the claudin family is an integral membrane protein and a component of tight junction strands Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome

Catalog No. 50-000-05180 Supplier ABclonal Technology Supplier No. A2197120UL
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Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet with complementary grooves in the inwardly facing extracytoplasmic leaflet The protein encoded by this gene a member of the claudin family is an integral membrane protein and a component of tight junction strands Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome

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