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ABclonal Technology KO Validated HIF1AN/FIH-1

Supplier: ABclonal Technology A27299100UL
Enables several functions including 2-oxoglutarate-dependent dioxygenase activity NF-kappaB binding activity and transition metal ion binding activity Involved in several processes including negative regulation of Notch signaling pathway negative regulation of transcription from RNA polymerase II promoter in response to hypoxia and protein hydroxylation Located in cytosol nucleoplasm and perinuclear region of cytoplasm Colocalizes with nucleus
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