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ABclonal Technology KO Validated SMARCB1/SNF5

Supplier: ABclonal Technology A23466100UL
The protein encoded by this gene is part of a complex that relieves repressive chromatin structures allowing the transcriptional machinery to access its targets more effectively The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase This gene has been found to be a tumor suppressor and mutations in it have been associated with malignant rhabdoid tumors Alternatively spliced transcript variants have been found for this gene
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