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Medchemexpress LLC KP-457 | 1365803-52-6 | 99.18% | 480.55 | 10 MG
SDP

Catalog No. 5000343594
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KP-457 is a selective a disintegrin and metalloproteinase 17 (ADAM17) inhibitor, demonstrating higher selectivity for ADAM17 than for other MMPs and ADAM10. It functions by blocking Zn2+ chelation of the catalytic domain of ADAM17.

  • Selective ADAM17 inhibitor
  • Blocks Zn2+ chelation of ADAM17 catalytic domain
  • Retains GPIbα expression on iPSC-derived platelets
  • Supports good hemostatic function in iPSC platelets

Catalog No. 50-003-43594 Supplier Medchemexpress LLC Supplier No. HY11039710MG
May include imposed supplier surcharges.
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KP-457 is a selective a disintegrin and metalloproteinase 17 (ADAM17) inhibitor, demonstrating higher selectivity for ADAM17 than for other MMPs and ADAM10. It functions by blocking Zn2+ chelation of the catalytic domain of ADAM17.

  • Selective ADAM17 inhibitor
  • Blocks Zn2+ chelation of ADAM17 catalytic domain
  • Retains GPIbα expression on iPSC-derived platelets
  • Supports good hemostatic function in iPSC platelets

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