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ABclonal Technology KPNB1 Rabbit mAb
SDP

Catalog No. 5000007864
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Nucleocytoplasmic transport which requires energy and signals occurs through nuclear pore complexes in the nuclear envelope Import of proteins with a nuclear localization signal (NLS) involves the NLS import receptor a heterodimer of importin alpha and beta subunits (karyopherins) Importin alpha binds the NLS cargo in the cytoplasm and importin beta docks the complex at the nuclear pore With nucleoside triphosphates and Ran GTPase the complex enters the pore dissociating into importin alpha and beta Importin alpha carries the cargo into the nucleoplasm while importin beta stays at the pore Importin beta interacts with FG repeats of nucleoporins to aid translocation This gene encodes a member of the importin beta family with two splice variants encoding different isoforms

Catalog No. 50-000-07864 Supplier ABclonal Technology Supplier No. A23235100UL
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Nucleocytoplasmic transport which requires energy and signals occurs through nuclear pore complexes in the nuclear envelope Import of proteins with a nuclear localization signal (NLS) involves the NLS import receptor a heterodimer of importin alpha and beta subunits (karyopherins) Importin alpha binds the NLS cargo in the cytoplasm and importin beta docks the complex at the nuclear pore With nucleoside triphosphates and Ran GTPase the complex enters the pore dissociating into importin alpha and beta Importin alpha carries the cargo into the nucleoplasm while importin beta stays at the pore Importin beta interacts with FG repeats of nucleoporins to aid translocation This gene encodes a member of the importin beta family with two splice variants encoding different isoforms

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