Medchemexpress LLC KRAS G12C inhibitor 14 | 2349393-95-7 | 99.0% | 484.88 | C24H19ClF2N4O3 | 10MM 1ML

Supplier:  Medchemexpress LLC HY12587210MM 1ML

KRAS G12C inhibitor 14 (Compound 17) is a potent small-molecule inhibitor selective for the KRAS G12C mutant (reported IC50 = 18 nM). It is supplied as a solid and as a 10 mM solution in DMSO for research use and is suitable for in vitro and in vivo studies of KRAS-driven signaling.

• Potency: IC50 = 18 nM against KRAS G12C.
• Molecular formula: C24H19ClF2N4O3; molecular weight: 484.88 g/mol.
• Purity: 99.0%.
• Available formats: solid (1 mg-500 mg) and 10 mM, 1 mL solution in DMSO.
• Solubility: DMSO 100 mg/mL; in vivo formulation yields ≥9 mg/mL in 10% DMSO/40% PEG300/5% Tween-80/45% saline.
• Storage: solid at -20°C; stock solution -80°C (6 months) or -20°C (1 month); protect from light and avoid repeated freeze-thaw.

Catalog No. 50-002-35600