Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC KRN2 bromide | 1390654-28-0 | 98.8% | 524.38 | 1 ML
Supplier: Medchemexpress LLC HY112125A10MM/1ML
KRN2 (bromide) is a selective inhibitor of nuclear factor of activated T cells (NFAT5), with an IC50 of 0.1 μM. It is for research use only and not sold to patients.
- Selectively suppresses the expression of pro-inflammatory genes, including Nos2 and Il6.
- Dose-dependently inhibits the NF-κB p65 binding to Nfat5 promoter 1.
- Directly blocks the interaction between NF-κB p65 and its DNA binding sequence.
- Effectively suppresses AIA and CIA in mice.
- Decreases the production of pro-inflammatory cytokines and autoantibodies.
- Reduces macrophage infiltration.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?