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Selleck Chemical LLC KT 474-E1655-1MG
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Supplier:  Selleck Chemical LLC E16551MG

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KT-474 (SAR444656) is a selective small-molecule degrader of IRAK4 in development for the treatment of TLR/IL-1R driven autoimmune diseases KT-474 potently downregulates R848 (TLR7/8) and lipopolysaccharide (LPS)-induced IL-6 and IL-8 production in peripheral blood mononuclear cells (PBMCs)

Catalog No. 50-313-4500


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