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Abcam KU-55933, competitive ATM kinase inhibitor, 10MG

Catalog No. 502707406
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MW 395.5 Da, Purity >99%. Potent, selective and competitive ATM kinase inhibitor. IC₅₀ values are 12.9 (ATM), 2000 (DNA-PK), 9300 (mTOR), 16600 (PI3K), >100000 (ATR) and >100000 nM (PI4K). Sensitizes cells to ionizing radiation and chemotherapeutics. Blocks Akt phosphorylation, induces G1 cell cycle arrest and induces apoptosis in breast and prostate cell lines.

The product is subject to the following: Abcam Restricted Use Statement

Catalog No. 50-270-7406 Supplier Abcam Supplier No. AB12063710MG
May include imposed supplier surcharges.
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MW 395.5 Da, Purity >99%. Potent, selective and competitive ATM kinase inhibitor. IC₅₀ values are 12.9 (ATM), 2000 (DNA-PK), 9300 (mTOR), 16600 (PI3K), >100000 (ATR) and >100000 nM (PI4K). Sensitizes cells to ionizing radiation and chemotherapeutics. Blocks Akt phosphorylation, induces G1 cell cycle arrest and induces apoptosis in breast and prostate cell lines.

The product is subject to the following: Abcam Restricted Use Statement

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