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Abcam KU-55933, competitive ATM kinase inhibitor, 10MG
Supplier: Abcam AB12063710MG
MW 395.5 Da, Purity >99%. Potent, selective and competitive ATM kinase inhibitor. IC₅₀ values are 12.9 (ATM), 2000 (DNA-PK), 9300 (mTOR), 16600 (PI3K), >100000 (ATR) and >100000 nM (PI4K). Sensitizes cells to ionizing radiation and chemotherapeutics. Blocks Akt phosphorylation, induces G1 cell cycle arrest and induces apoptosis in breast and prostate cell lines.
The product is subject to the following: Abcam Restricted Use Statement
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