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Medchemexpress LLC KVA-D-88 | 2410550-31-9 | 99.8% | 382.19 | 1 ML
SDP

Catalog No. 5000350753
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KVA-D-88 is a blood-brain barrier-permeable PDE4 inhibitor with IC50 values of 140 and 880 nM for PDE4B and PDE4D, respectively. It inhibits cocaine-induced hyperlocomotor activity and sensitization, selectively inhibiting PDE4B and reducing cAMP degradation, thereby modulating neuroadaptive responses. It can be used in the study of cocaine addiction.

  • Blood-brain barrier-permeable PDE4 inhibitor
  • Inhibits cocaine-induced hyperlocomotor activity and sensitization
  • Selectively inhibits PDE4B and reduces cAMP degradation
  • Modulates neuroadaptive responses
  • Useful in the study of cocaine addiction

Catalog No. 50-003-50753 Supplier Medchemexpress LLC Supplier No. HY13917810MM/1ML
May include imposed supplier surcharges.
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KVA-D-88 is a blood-brain barrier-permeable PDE4 inhibitor with IC50 values of 140 and 880 nM for PDE4B and PDE4D, respectively. It inhibits cocaine-induced hyperlocomotor activity and sensitization, selectively inhibiting PDE4B and reducing cAMP degradation, thereby modulating neuroadaptive responses. It can be used in the study of cocaine addiction.

  • Blood-brain barrier-permeable PDE4 inhibitor
  • Inhibits cocaine-induced hyperlocomotor activity and sensitization
  • Selectively inhibits PDE4B and reduces cAMP degradation
  • Modulates neuroadaptive responses
  • Useful in the study of cocaine addiction

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