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Medchemexpress LLC KVA-D-88 | 2410550-31-9 | 99.81% | 382.19 | 25 MG
SDP

Catalog No. 5000349546
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KVA-D-88 is a blood-brain barrier-permeable PDE4 inhibitor with IC50 values of 140 nM for PDE4B and 880 nM for PDE4D. It inhibits cocaine-induced hyperlocomotor activity and sensitization by selectively inhibiting PDE4B and reducing cAMP degradation, thereby modulating neuroadaptive responses. This compound can be utilized in the study of cocaine addiction.

  • Blood-brain barrier-permeable PDE4 inhibitor
  • Selectively inhibits PDE4B and reduces cAMP degradation
  • Modulates neuroadaptive responses
  • Inhibits cocaine-induced hyperlocomotor activity and sensitization
  • Useful in the study of cocaine addiction

Catalog No. 50-003-49546 Supplier Medchemexpress LLC Supplier No. 25MGHY139178
May include imposed supplier surcharges.
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KVA-D-88 is a blood-brain barrier-permeable PDE4 inhibitor with IC50 values of 140 nM for PDE4B and 880 nM for PDE4D. It inhibits cocaine-induced hyperlocomotor activity and sensitization by selectively inhibiting PDE4B and reducing cAMP degradation, thereby modulating neuroadaptive responses. This compound can be utilized in the study of cocaine addiction.

  • Blood-brain barrier-permeable PDE4 inhibitor
  • Selectively inhibits PDE4B and reduces cAMP degradation
  • Modulates neuroadaptive responses
  • Inhibits cocaine-induced hyperlocomotor activity and sensitization
  • Useful in the study of cocaine addiction

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