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TARGETMOL CHEMICALS INC KW-2450 free base 1MG
Supplier: TARGETMOL CHEMICALS INC T684051MG
Also available in 2 mg, 5 mg, 10 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. KW-2450 free base is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity. IGF-1R/IR inhibitor KW-2450 free base selectively binds to and inhibits the activities of IGF-1R and IR, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. IGF-R1 and IR tyrosine kinases, overexpressed in a variety of human cancers, play significant roles in the stimulation of cellular proliferation, oncogenic transformation, and suppression of apoptosis. Purity 99.11%
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