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Apexbio Technology LLC L-161,982(Synonyms: L-161982, L161982, EP4 Receptor Antagonist L-161982, EP4 antagonist L-161982), 1mg, CAS: 147776-06-5.
Supplier: Apexbio Technology LLC B70881
L-161 982 (CAS 147776-06-5) is a selective antagonist of the prostaglandin E2 receptor subtype EP4 By specifically blocking EP4 signaling this compound modulates downstream pathways associated with inflammation and cell proliferation In vitro studies indicate that inhibition of EP4 by L-161 982 reduces ERK phosphorylation and consequently suppresses proliferation of the HCA-7 cell line Additionally rodent studies demonstrate that L-161 982 alleviates collagen-induced arthritis underscoring its utility in investigating EP4-related inflammatory processes and disease mechanisms
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