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Medchemexpress LLC L-161982 | 147776-06-5 | 99.3% | 654.72 | 10 MG
SDP

Catalog No. 5000346453
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L-161982 is a selective EP4 receptor antagonist. It completely blocks PGE2-induced ERK phosphorylation and cell proliferation of HCA-7 cells. L-161982 alleviates collagen-induced arthritis in mice.

  • Selective EP4 receptor antagonist
  • Completely blocks PGE2-induced ERK phosphorylation and cell proliferation of HCA-7 cells
  • Alleviates collagen-induced arthritis in mice
  • Induces apoptosis, cell cycle arrest, and inhibits prostaglandin E2-induced proliferation in oral squamous carcinoma Tca8113 cells
  • Reduces arthritis lesions and lesion progression in CIA mice

Catalog No. 50-003-46453 Supplier Medchemexpress LLC Supplier No. HY10855910MM/1ML
May include imposed supplier surcharges.
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L-161982 is a selective EP4 receptor antagonist. It completely blocks PGE2-induced ERK phosphorylation and cell proliferation of HCA-7 cells. L-161982 alleviates collagen-induced arthritis in mice.

  • Selective EP4 receptor antagonist
  • Completely blocks PGE2-induced ERK phosphorylation and cell proliferation of HCA-7 cells
  • Alleviates collagen-induced arthritis in mice
  • Induces apoptosis, cell cycle arrest, and inhibits prostaglandin E2-induced proliferation in oral squamous carcinoma Tca8113 cells
  • Reduces arthritis lesions and lesion progression in CIA mice

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