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Apexbio Technology LLC L-a-Hydroxyglutaric acid disodium salt(Synonyms: Disodium L-alpha-hydroxyglutarate, L-alpha-Hydroxyglutaric acid disodium salt), 10mg, CAS: 63512-50-5.
Supplier: Apexbio Technology LLC A160610
L-a-Hydroxyglutaric acid disodium salt (CAS 63512-50-5) is a salt derivative of L- -hydroxyglutaric acid a metabolite implicated in the rare condition L- -hydroxyglutaric aciduria due to dysfunction of L-2-hydroxyglutarate dehydrogenase It is employed experimentally to enhance stabilization and recovery yield of hypoxia-inducible factor-1 (HIF-1 ) a recognized indicator of tumor hypoxia Additionally it functions as a research tool in enzymatic assays evaluating modulation of TET family methylcytosine dioxygenases In animal models the compound promotes oxidative stress evidenced by elevated brain chemiluminescence and lipid peroxidation effects mitigated by antioxidant treatments Currently this molecule remains in preclinical investigational stages
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