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Medchemexpress LLC L-2-hydroxyglutaric acid | 13095-48-2 | 95.1% | 148.11 | 10 MG
SDP

Catalog No. 5000439839
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L-2-Hydroxyglutaric acid is an epigenetic modifier and putative oncometabolite in renal cancer. It can inhibit histone demethylases, thereby promoting histone methylation. L-2-Hydroxyglutaric acid also inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki values of 2.52 mM and 11.13 mM, respectively. It is potent at inhibiting 2-oxoglutarate (2-OG) dependent dioxygenases (2OGDs) including the Ten Eleven Translocation (TET) enzymes.

  • Epigenetic modifier
  • Putative oncometabolite in renal cancer
  • Inhibits histone demethylases
  • Inhibits mitochondrial creatine kinase (Mi-CK) activity
  • Potent at inhibiting 2-oxoglutarate (2-OG) dependent dioxygenases (2OGDs)
  • Human endogenous metabolite

Catalog No. 50-004-39839 Supplier Medchemexpress LLC Supplier No. HY11303910MG
May include imposed supplier surcharges.
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L-2-Hydroxyglutaric acid is an epigenetic modifier and putative oncometabolite in renal cancer. It can inhibit histone demethylases, thereby promoting histone methylation. L-2-Hydroxyglutaric acid also inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki values of 2.52 mM and 11.13 mM, respectively. It is potent at inhibiting 2-oxoglutarate (2-OG) dependent dioxygenases (2OGDs) including the Ten Eleven Translocation (TET) enzymes.

  • Epigenetic modifier
  • Putative oncometabolite in renal cancer
  • Inhibits histone demethylases
  • Inhibits mitochondrial creatine kinase (Mi-CK) activity
  • Potent at inhibiting 2-oxoglutarate (2-OG) dependent dioxygenases (2OGDs)
  • Human endogenous metabolite

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