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Medchemexpress LLC L-372662 | 162045-26-3 | C₃₃H₃₈N₄O₆ | 5 MG
Supplier: Medchemexpress LLC HY150115MG
L-372662 is a potent and orally active non-peptide oxytocin antagonist with a Ki value of 4.8. It demonstrates selectivity to OTR:V1aR and acts as an antagonist of oxytocin-induced uterine contractions. This compound exhibits good oral bioavailability and aqueous solubility.
- Potent and orally active non-peptide oxytocin antagonist
- Ki value of 4.8
- Kd value for wild-type hOTR is 5.8 nM
- Kd value for [A318G]OTR is 73 nM
- Selectivity to OTR:V1aR
- Antagonist of oxytocin-induced uterine contractions
- Oral bioavailability (F = 90% in dogs)
- Aqueous solubility (10 mg/mL)
- For research use only
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