Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000365247

Medchemexpress LLC L-733060 hydrochloride | 148687-76-7 | 99.9% | 439.82 | 1 MG
SDP

Catalog No. 5000365247
Encompass_Preferred

L-733060 hydrochloride is a selective neurokinin-1 (NK-1) receptor antagonist. It primarily regulates pain transmission and neural plasticity by blocking the binding of Substance P to the NK-1 receptor. It blocks the promoting effect of Substance P on long-term potentiation (LTP) in the hippocampus and reverses orofacial hyperalgesia induced by experimental occlusal interference (EOI) in rats. Additionally, it inhibits neurogenic plasma extravasation and acts as an anti-tumor agent, making it suitable for studying chronic orofacial pain.

  • Selective neurokinin-1 (NK-1) receptor antagonist
  • Regulates pain transmission and neural plasticity
  • Blocks Substance P binding to NK-1 receptor
  • Reverses orofacial hyperalgesia
  • Inhibits neurogenic plasma extravasation
  • Acts as an anti-tumor agent
  • Suitable for studying chronic orofacial pain

Catalog No. 50-003-65247 Supplier Medchemexpress LLC Supplier No. 1MGHY14406A
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

L-733060 hydrochloride is a selective neurokinin-1 (NK-1) receptor antagonist. It primarily regulates pain transmission and neural plasticity by blocking the binding of Substance P to the NK-1 receptor. It blocks the promoting effect of Substance P on long-term potentiation (LTP) in the hippocampus and reverses orofacial hyperalgesia induced by experimental occlusal interference (EOI) in rats. Additionally, it inhibits neurogenic plasma extravasation and acts as an anti-tumor agent, making it suitable for studying chronic orofacial pain.

  • Selective neurokinin-1 (NK-1) receptor antagonist
  • Regulates pain transmission and neural plasticity
  • Blocks Substance P binding to NK-1 receptor
  • Reverses orofacial hyperalgesia
  • Inhibits neurogenic plasma extravasation
  • Acts as an anti-tumor agent
  • Suitable for studying chronic orofacial pain

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.