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Medchemexpress LLC L-745870 hydrochloride | 1173023-36-3 | MFCD01529971 | 99.9% | C18H20Cl2N4 | 100 MG
SDP

Catalog No. 5000355541
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L-745870 hydrochloride is a potent, selective, brain-penetrant, and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. It demonstrates weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites, and α-adrenoceptors. This product is intended for research use only.

  • Potent, selective, brain-penetrant, and orally active dopamine D4 receptor antagonist
  • Weaker affinity for D2 and D3 receptors
  • Moderate affinity for 5-HT2 receptors, sigma sites, and α-adrenoceptors
  • Good pharmacokinetic properties in rat and monkey
  • Excellent brain penetration with high brain to plasma ratios in rats

Catalog No. 50-003-55541 Supplier Medchemexpress LLC Supplier No. HY14325B100MG
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L-745870 hydrochloride is a potent, selective, brain-penetrant, and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. It demonstrates weaker affinity for D2 (Ki of 960 nM) and D3 (Ki of 2300 nM) receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites, and α-adrenoceptors. This product is intended for research use only.

  • Potent, selective, brain-penetrant, and orally active dopamine D4 receptor antagonist
  • Weaker affinity for D2 and D3 receptors
  • Moderate affinity for 5-HT2 receptors, sigma sites, and α-adrenoceptors
  • Good pharmacokinetic properties in rat and monkey
  • Excellent brain penetration with high brain to plasma ratios in rats

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