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Medchemexpress LLC L-803087 | 217480-26-7 | 99.7% | 485.53 | 1 MG
Supplier: Medchemexpress LLC HY10849750MG
L-803087 is a potent and selective somatostatin sst4 receptor agonist with a Ki of 0.7 nM. It is >280-fold more selective than other somatostatin receptors. This compound facilitates AMPA-mediated hippocampal synaptic responses in vitro and increases kainate-induced seizures in mice.
- Potent and selective somatostatin sst4 receptor agonist.
- Greater than 280-fold higher selectivity for sst4 receptor compared to other somatostatin receptors.
- Facilitates AMPA-mediated hippocampal synaptic responses in vitro.
- Increases kainate-induced seizures in mice.
- Does not inhibit secretion of growth hormone, insulin, or glucagon.
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