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Medchemexpress LLC L-803087 | 217480-26-7 | 99.7% | 485.53 | 50 MG
Supplier: Medchemexpress LLC HY1084971MG
L-803087 is a potent and selective somatostatin sst4 receptor agonist with a Ki of 0.7 nM. It demonstrates >280-fold higher selectivity for the sst4 receptor compared to other somatostatin receptors, facilitating AMPA-mediated hippocampal synaptic responses in vitro and increasing kainate-induced seizures in mice. The compound has a diamine moiety and does not inhibit the secretion of growth hormone, insulin, or glucagon.
- Potent and selective somatostatin sst4 receptor agonist
- Ki of 0.7 nM for sst4 receptor
- Facilitates AMPA-mediated hippocampal synaptic responses in vitro
- Increases kainate-induced seizures in mice
- Does not inhibit the secretion of growth hormone, insulin, or glucagon
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