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Medchemexpress LLC L-Azetidine-2-carboxylic acid | 2133-34-8 | 99.9% | 101.10 | 500 MG
Supplier: Medchemexpress LLC 500MGHYW050044
L-Azetidine-2-carboxylic acid is a proline analog that influences cellular processes such as lipid autophagy and endoplasmic reticulum stress. It is known to upregulate the lipid autophagy marker LC3-II and increase pro-apoptotic BAX protein, while also inducing ATF6 cleavage and upregulating phosphorylated eIF2α levels. This compound induces ER stress, leading to protein misfolding and aggregation, and has demonstrated teratogenic, pro-inflammatory, and pro-apoptotic effects.
- Upregulates the lipid autophagy marker LC3-II via activation of the PERK pathway.
- Increases pro-apoptotic BAX protein.
- Induces ATF6 cleavage and upregulates phosphorylated eIF2α levels.
- Induces ER stress, leading to protein misfolding and aggregation.
- Shows teratogenic, pro-inflammatory, and pro-apoptotic effects.
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