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Medchemexpress LLC L-Glutamic acid, 1,5-bis(1,1-dimethylethyl) ester, hydrochloride (1:1) | 32677-01-3 | 98.0% | 295.80 | 25 G

Supplier: Medchemexpress LLC 25GHY20167A
H-Glu(OtBu)-OtBu hydrochloride is a key intermediate utilized in the synthesis of prostate-specific membrane antigen (PSMA) targeting probes. It can reduce nonspecific background binding via negatively charged linkers, thereby improving tumor/background contrast, and is applicable in prostate cancer PET/SPECT imaging studies.
- Used to synthesize prostate-specific membrane antigen targeting probes.
- Can reduce nonspecific background binding through negatively charged linkers.
- Enhances tumor/background contrast.
- Can be used in prostate cancer PET/SPECT imaging studies.
- Can be used to synthesize PSMA probe 5, which was labeled with 18F for tumor imaging, showing significant tumor uptake (4.6% ID/g) and low background (0.04% ID/g) in PET imaging experiments with PC3-PIP tumors.
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