L-Histidine, MP Biomedicals™

Description

Functions as a precursor of histamine by action of histidine decarboxylase. L-Histidine, MP Biomedicals is an essential amino acid with a basic side chain that contains an imidazole group. It is hydrophilic in character. It is generally used in media prep

Histidine is biosynthesized from ATP, 5-phosphoribosyl-1-pyrophosphate (PRPP), and glutamine. In turn, histidine is degraded to glutamate by histidase, urocanase, and imidazolonepropionase via the formation of urocanate, 4-imidazolone 5-propionate, and N-formiminoglutamate.

• Has been used to study cultures of the human T-lymphoblastic leukemia cell line MOLT-4 to study modulation of apoptosis
• Has been shown to enhance the biosynthesis of lovastatin by cultured Aspergillus terreus
• Utilized as a single nitrogen source to probe swarming in Pseudomonas aeruginosa on agar

Specifications

Chemical Identifiers

• CAS: 71-00-1
• Molecular Formula: C6H9N3O2
• Molecular Weight (g/mol): 155.16
• MDL Number: MFCD00064315
• InChI Key: HNDVDQJCIGZPNO-UHFFFAOYNA-N
• Synonym: l-histidine, histidine, h-his-oh, glyoxaline-5-alanine, anti-rheuma, l---histidine, istidina, s-histidine, l-histidin
• PubChem CID: 6274
• ChEBI: CHEBI:15971
• IUPAC Name: (2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid
• SMILES: NC(CC1=CN=CN1)C(O)=O

• Solubility Information: Soluble 50mg/mL in 0.5 M HCl.
• Quantity: 10 g
• Formula Weight: 155.2
• Percent Purity: ≥99%
• Physical Form: Crystalline Powder

Safety and Handling

Recommended Storage

Store at Room Temperature (15–30°C)