Medchemexpress LLC L-NAME hydrochloride (NG-Nitroarginine methyl ester hydrochloride) | 51298-62-5 | 99.9% | 269.69 | 500 MG

Supplier:  Medchemexpress LLC HY18729A500MG

L-NAME hydrochloride is a nitric oxide synthase (NOS) inhibitor with an IC50 of 70 μM. It acts as a precursor to the more potent NOS inhibitor L-NOARG (IC50 of 1.4 μM), making it valuable in studies of L-arginine analogues that inhibit NOS activity. Its efficacy can increase with prolonged incubation at neutral or alkaline pH, correlating with its hydrolysis to L-NOARG. This compound is also used to induce hypertension and preeclampsia models in animal studies.

• Inhibits NOS with an IC50 of 70 μM.
• Precursor to NOS inhibitor L-NOARG.
• Used to induce hypertension and preeclampsia models in animal studies.
• Appearance: solid, white to off-white.
• Storage: -20°C, sealed, away from moisture.
• In solvent: -80°C for 6 months; -20°C for 1 month.

Catalog No. 50-003-86066