Apexbio Technology LLC L-Phenylephrine 59-42-7 10g

Supplier:  Apexbio Technology LLC C302110000

L-Phenylephrine (CAS 59-42-7) is a selective agonist of the adrenergic 1A receptor exhibiting a Ki of 1 4 M with markedly lower affinity for 1B (Ki 23 9 M) and 1C (Ki 47 8 M) subtypes In vitro L-Phenylephrine has been shown to reduce apoptosis in neonatal rat cardiomyocytes following hypoxia and serum deprivation and to stimulate proliferation in neural progenitor cells It also increases the cross-sectional area and modulates gene expression in rat neonatal cardiomyocytes In vivo local administration in rats induces cutaneous anesthesia through 1-adrenergic receptor activation and clinical data suggest oral administration reduces nasal airway resistance These properties make L-Phenylephrine a valuable tool for studying 1A-adrenergic receptor-mediated cellular responses

Catalog No. 50-000-87939