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Cayman Chemical L-PyrohomoglutamIc AcId 1g

Supplier: Cayman Chemical 316941 G

An amide originally isolated from P aurantiacum that has diverse biological activities including anti-inflammatory antibacterial antioxidant and anticancer properties inhibits production of NO PGE2 and IL-1B in LPS-stimulated BV-2 microglial cells (IC50s 49 7 51 5 and 40 4 UM respectively) active against Gram-negative bacteria (MICs 0 05-0 10 mg/ml) has antioxidant activity in DPPH and TEAC assays (EC50s 9 51-78 81 Ug/ml) decreases viability of U87 and U251 cancer cell in vitro when used at 10 to 100 UM reduces tumor growth at 1 mg via intratumoral injection in a U87 mouse xenograft model
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