Medchemexpress LLC L-tryptophanamide, n-((3-methyl-1h-inden-2-yl)carbonyl)-d-alanyl | 1416709-79-9 | 98.9% | 618.72 g·mol⁻¹ | C37H38N4O5 | 10MG

Supplier:  Medchemexpress LLC HY12358710MG

PR-924 is a selective tripeptide epoxyketone inhibitor of the immunoproteasome subunit LMP-7, reported to inhibit LMP-7 with an IC50 of 22 nM and to induce antiproliferative and proapoptotic effects in multiple myeloma cells. It covalently modifies the proteasomal N-terminal threonine active site and is supplied as an off-white to light yellow solid for research use.

• Selective LMP-7 immunoproteasome inhibitor (IC50 = 22 nM).
• Covalently modifies proteasomal N-terminal threonine active sites.
• Molecular formula C37H38N4O5; molecular weight 618.72 g·mol⁻¹.
• High purity (~98.9%).
• Recommended solvent DMSO; solubility ~50 mg/mL with ultrasonic assistance.
• Powder storage: -20°C for long term; in solution store at -80°C for extended periods.

Catalog No. 50-002-37055