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AdipoGen Lactacystin

Supplier: AdipoGen AGCN20104M001
Chemical. CAS 133343-34-7. Formula C15H24N2O7S. MW 376.4. Isolated from Streptomyces lactacystinnaeus strain OM-6519. Induces neuritogenesis. Potent and selective irreversible proteasome inhibitor. Specifically inhibits 20S proteasome MCP multicatalytic complex. Blocks proteasome activity by targeting the catalytic beta-subunit. Apoptosis inducer. Anticancer compound. Upregulates HSP70 and HSP22. Induces differentiation and inhibits cell cycle progression in several tumor cell lines. Inhibits NF-kappaB activation by inhibiting IkappaB degradation. Cathepsin A inhibitor. beta-Secretase activity inhibitor. Anti-adipogenic. Autophagy inducer.
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