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Medchemexpress LLC Ladarixin sodium | 865625-56-5 | 99.8% | 397.32 | 1 ML
SDP

Catalog No. 5000401790
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Ladarixin sodium is an orally active, allosteric non-competitive, and dual CXCR1 and CXCR2 antagonist. It can be used for the research of COPD and asthma.

  • Orally active
  • Allosteric non-competitive antagonist
  • Dual CXCR1 and CXCR2 antagonist
  • Inhibits human polymorphonuclear leukocyte (PMN) migration to CXCL8
  • Reduces allergic airway inflammation in single OVA exposure models
  • Reduces allergic airway inflammation, remodeling, and bronchial hyperreactivity in chronic OVA exposure models
  • Reduces pulmonary inflammation and fibrosis induced by bleomycin in mice
  • Protects mice from cigarette smoke-induced exacerbation of influenza-A infection
  • Effective in decreasing CXCL8-induced polymorphonuclear leukocyte infiltration in several animal models

Catalog No. 50-004-01790 Supplier Medchemexpress LLC Supplier No. HY19519A10MM/1ML
May include imposed supplier surcharges.
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Ladarixin sodium is an orally active, allosteric non-competitive, and dual CXCR1 and CXCR2 antagonist. It can be used for the research of COPD and asthma.

  • Orally active
  • Allosteric non-competitive antagonist
  • Dual CXCR1 and CXCR2 antagonist
  • Inhibits human polymorphonuclear leukocyte (PMN) migration to CXCL8
  • Reduces allergic airway inflammation in single OVA exposure models
  • Reduces allergic airway inflammation, remodeling, and bronchial hyperreactivity in chronic OVA exposure models
  • Reduces pulmonary inflammation and fibrosis induced by bleomycin in mice
  • Protects mice from cigarette smoke-induced exacerbation of influenza-A infection
  • Effective in decreasing CXCL8-induced polymorphonuclear leukocyte infiltration in several animal models

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