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Biogenex Laboratories Lambda Light Chain: Poly :6mL
Supplier: Biogenex Laboratories AR0495R
The light chains of immunoglobulin molecules may be either Kappa or Lambda The clonal nature of any immunoglobulin-producing cell population can be determined by its light chain structure. Lambda chains are expressed on the surface of B-cells. Antibodies to kappa and lambda light chains are used for the evaluation of leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas, the majority of which are derived from B-cell lineage. The most important uses of this technique would be in distinguishing atypical reactive follicular lymphoid hyperplasia from follicular lymphoma, undifferentiated carcinoma from large cell lymphoma, pseudolymphoma from lymphoma, and reactive plasmacytosis from well differentiated plasmacytoma.
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